South of Los Angeles, bordering Mexico and the Pacific Ocean, San Diego is the 2nd largest city in California and the 8th largest city in the US. While it has recently emerged as a development center for healthcare and biotechnology, San Diego is most well-known for its extensive beaches, deep water harbor, mild year-round climate and a long-standing association with the US Navy. San Diego's main economic activities consist of: manufacturing, international trade, tourism, and military and defense related activities. In addition to this, is also steeped in rich historical significance since it was discovered in 1542 and claimed for Spain.
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